Greetings, I hope this letter finds you well. I wish share with you an effective treatment for chronic nocturia I. a patient, have found after having tried every other form of treatment. I want to share my solution to nocturia with you and other patients. I suffer from the worst case of nocturia either of my two urologists have seen. I would literally get up nearly every hour of the night with an urge to urinate even the tiniest amount of urine. It was hellish. I would generally be able to finally fall asleep for maybe 2 or 2 ½ hours straight some time about 2:00 or 3:00 AM. I would be exhausted in the morning and would require day time naps. It ruined my quality of life. Please keep in mind that I did all the life style changes and kept a urinary log to tract my night time voids. Prior to finding the three drug treatment listed below the only way I could sleep for more than 2 hours a night was to drink alcohol in excess (i.e.- getting drunk). Alcohol was the only useful form of treatment, but a flawed one.
My urologists tried every form of treatment on me with very little or no success, which I will detail below. But first let me cut to the chase and tell you the very effective course of treatment I have found only after 3 years of constant trial and error.
AN EFFECTIVE TREATMENT FOR NOCTURIA THAT WORKS!
The following has been very effective for me and I hope you will share it with other patients. At bed time I take the following:
1. Trazadone 50 or 100 mg
2. Gabapentin 300mg
3. Melatonin 5mg
HERE ARE ALL MY FAILED TREATMENTS:
Let me detail all the treatments I have tried without success. First there was Transurethral resection of the prostate (TURP surgery), its 80% effective in treating over active bladder in men, but unlucky me I was in the other 20%.
Next there was OnabotulinumtoxinA (ON-ah-boch-yoo-lih-num-tox-in-A), also called Botox injections to the bladder. I had it done 3 times. The first dose of 100 ml really seemed to help in that it allowed me to sleep for an amazing 2 hours at a time without having to get up to pee. Please note that for me my condition was so bad that being able to sleep for 2 hours straight was considered a great victory. However, once the first dose wore off the two subsequent dosed did nothing even though we doubled the dose to 200 ml!
Then there was Percutaneous tibial nerve stimulation (PTNS) which is a form of acupuncture for 12 weeks. Nope, it did not work at all for me!
Then we tried Sacral nerve stimulation (SNS): SNS which uses the same principle as PTNS. Nope, did not work for me!
Then we of course tried all the drugs recommended to treat over active bladder. In summary they either had nasty side affects that caused me to stop taking them or they did not improve my symptoms. Here is a list of all the drugs I tried unsuccessfully.
• Oxybutynin (Ditropan XL)
• Trospium (Sanctura)
• Solifenacin (Vesicare)
• Darifenacin (Enablex) Flowmax
• Trospium 20 mg
• Tadalafil (Cialis)
I was so desperate. I even tried herbal remedies like Ganoderma lucidum, corn silk, magnesium, Capsaicin and Pumpkin seeds. All these had no positive affect. It got to the point where one of my urologist suggested removing my bladder as a final course of treatment. I declined.
ACCIDEENTLY DISCOVERING AN EFFECTIVE TREATMENT:
I was at a total loss and felt there would never be any hope of treating my nocturia and being able to sleep at night. Until I suffered from a painful pinched nerve in my neck for a week. I went to my family doctor who prescribed me 300mg of Gabapentin. The Gabapentin did nothing to help my neck pain, but I noticed it significantly reduced the number times per night I needed to void. I was actually able to get some sleep! So, I did some research online and found articles about the successful use of Gabapentin in experiments to treat nocturia. Why didn’t my two urologists know about them?
I then had to wonder if my condition was also not just a matter of over active bladder, but also difficulty falling asleep. My urologist recommended I take Ambien sleep medicine. My research revealed Ambien was habit forming and tended to make patients a little squirely in the head so I declined. I then ask my family doctor who suggested taking Trazadone 100mg, which is not habit forming. It works great! It really helped me sleep. I can now sleep for almost 5 hours straight on some nights. I usually only take 50mg of Trazadone as that is all I need. I take the over the counter med Melatonin 5mg, which also helps. Trazadone can NOT be taken with alcohol as there could be a very dangerous reaction and Trazadone also has the rare side effect of causing men to have erections that do not go done requiring emergency surgery to drain the blood from the penis before it turns to gangrene.
So there you have it. After 3 years of I finally found a way to affectively treat my nocturia on my own. There was one other thing that I believed really helped me. Prayer! I asked God to guide me in my search for a solution and he did. I hope this information can help someone.
639 Michelle Drive
Hedgesville, WV 25427